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Search Results for " c3/c5 convertase "

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Cat. No.	Product Name	Species	Expression System
TMPK-01268	Complement C2 Protein, Cynomolgus, Recombinant (His) C2,CO2,Complement C2,C3/C5 convertase<...	Cynomolgus	HEK293 Cells
	Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC.
TMPH-02607	Complement factor B Protein, Mouse, Recombinant (His) C3/C5 convertase,Complement facto...	Mouse	E. coli
	Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase.
TMPH-03038	Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) Cobra venom factor,Complement C3 homolog,CVFk,CVF	Naja kaouthia	E. coli
	Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re...
TMPH-02845	Properdin Protein, Mouse, Recombinant (His & Myc)	Mouse	HEK293 Cells
	A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
TMPH-02844	Properdin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes. Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b).
TMPJ-00149	Complement Factor D/CFD Protein, Mouse, Recombinant (His) C3 convertase activator,28 kDa adipocyte p...	Mouse	HEK293 Cells
	Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the...

重组蛋白

Complement C2 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-01268

Species: Cynomolgus

Expression System: HEK293 Cells

Complement factor B Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02607

Species: Mouse

Expression System: E. coli

Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)

Cat.No: TMPH-03038

Species: Naja kaouthia

Expression System: E. coli

Properdin Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02845

Species: Mouse

Expression System: HEK293 Cells

Properdin Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02844

Species: Mouse

Expression System: E. coli

Complement Factor D/CFD Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00149

Species: Mouse

Expression System: HEK293 Cells

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